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. Author manuscript; available in PMC: 2023 Apr 12.
Published in final edited form as: Glia. 2022 Sep 2;71(2):187–204. doi: 10.1002/glia.24266

Figure 10: Loss of oligodendrocyte ErbB signaling leads to reduction in A1 MBP immunostaining both associated and not associated with PV immunostaining.

Figure 10:

a, Representative photomicrographs of A1 sections from WT and CNP-DN-ErbB4 mice showing the area with PV immunostaining (left), the area with MBP immunostaining (middle) and the MBP+ area not associated with PV staining (right). Scale bar: 20μm.

b, Percent area covered by total MBP signal in A1 of WT (black) and CNP-DN-ErbB4 (red) mice (n = 6; p = 0.0043).

c, Percent area covered by MBP signal associated with PV signal (PV+ & MBP+) in A1 of WT (black) and CNP-DN-ErbB4 (red) mice (n = 6; p = 0.0022).

d, Percent area covered by MBP signal not associated with PV signal (PV− & MBP+) in A1 of WT (black) and CNP-DN-ErbB4 (red) mice (n = 6; p = 0.0087).

Mann-Whitney test was performed. Data are expressed as mean ± SEM.