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. Author manuscript; available in PMC: 2023 Apr 12.
Published in final edited form as: Glia. 2022 Sep 2;71(2):187–204. doi: 10.1002/glia.24266

Figure 11: Loss of oligodendrocyte ErbB signaling leads to reduction in PV+, but not GAD67+ synaptic terminals in A1.

Figure 11:

a, Representative photomicrographs of A1 sections from WT and CNP-DN-ErbB4 mice showing the GAD67 (red), the PV (green) and colocalized GAD67-PV (merge) perisomatic puncta. Scale bar: 10μm.

b, Number of GAD67+, PV+ and GAD67+-PV+ perisomatic puncta/100 μm in A1 of WT (black) and CNP-DN-ErbB4 (red) mice (n = 4 – 6; ** p = 0.0095; * p = 0.0190).

c, Percent % GAD67+ puncta that are also PV+ in A1 of WT (black) and CNP-DN-ErbB4 (red) mice (n = 4 – 6; p = 0.0381).

d, Percent % GAD67+ puncta that are not PV+ in A1 of WT (black) and CNP-DN-ErbB4 (red) mice (n = 4 – 6; p = 0.0381).

Mann-Whitney test was performed. Data are expressed as mean ± SEM.