Figure 13.

Example of early assessment of the response to NAC using diffusion weighted imaging (DWI). examinations; (A-C)= pre-NAC examinations; (D-F)= early assessment examination after two cycles of cytotoxic NAC. (A,D) = dynamic post-contrast images; (B,E) = DWI images; (C,F) = ADC maps. A 37-year-old patient with a G3, triple negative invasive ductal carcinoma of the right breast (white and black arrows). Early assessment showed a reduction of tumor size along with increase of signal intensity on ADC maps (C) compared to the pre-treatment examination (F). Pathology after surgical resection revealed pathological complete response (pCR). Reprinted under a Creative Commons (CC BY 4.0) license from: Romeo V, Accardo G, Perillo T, Basso L, Garbino N, Nicolai E, Maurea S, Salvatore M. Assessment and Prediction of Response to Neoadjuvant Chemotherapy in Breast Cancer: A Comparison of Imaging Modalities and Future Perspectives. Cancers (Basel). 2021 Jul 14;13(14):3521.