Figure 2. Genomic landscape of SB|Braf lung drivers.

A: Oncoprint of statistically significant drivers in BRAF^V600E-driven lung tumors detected using GKC analysis, using SB common integration regions (CIRs), and Truncal SB Driver Analysis, using unique, directional SB insertions at TA-dinucleotides.B: SB insertions at TA-dinucleotides with sense (red arrowhead) and anti-sense (blue arrowheads) and within CIRs (blue lines) for Foxp1 (3 transcripts of the genes are shown).C: SB insertions at TA-dinucleotides with sense (red arrowhead) and anti-sense (blue arrowheads) and within CIRs (blue lines) for Rbms3 (6 transcripts of the candidate gene are shown).