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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: Neuropsychopharmacology. 2010 Mar 31;35(8):1775–1787. doi: 10.1038/npp.2010.44

Figure 6.

Figure 6

Representative autoradiograms illustrating WIN55,212-2 stimulated [35S]GTPγS binding in brains from vehicle, THC- and AEA-treated FAAH−/− mice. WIN55,212-2-stimulated [35S]GTPγS binding is visibly reduced in FAAH−/− mice treated with THC in nearly all regions including caudate-putamen (top panels), globus pallidus (top center panels), PAG (bottom center panels), and cerebellum (bottom panels). AEA-treated FAAH−/− mice had intermediate levels of WIN55,212-2-stimulated [35S]GTPγS binding between vehicle and THC-treated mice. Data from densitometric analysis are presented in Table 4.