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Comparison of THC potency in FAAH−/− mice that were treated repeatedly with vehicle, THC, or AEA
| Subchronic Treatment | Antinociception | Catalepsy | Hypothermia |
|---|---|---|---|
| Vehicle | 20 (16-24) | 16 (13-19) | 17 (15-20) |
| THC | 76 (58-99) | 50% @ 150 mg/kg | 32 (27-38) |
| AEA | 55 (44-69) | 62 (56-69) | 50 (40-55) |
Data represent ED50 values (95% CI) or maximum effect ± SEM if efficacy < 70%, and are represented in mg/kg.
