. Author manuscript; available in PMC: 2011 Jan 1.

Published in final edited form as: Neuropsychopharmacology. 2010 Mar 31;35(8):1775–1787. doi: 10.1038/npp.2010.44

Table 5.

[³H]WIN55,212-2 binding in brain sections from vehicle-, THC-, and AEA-treated FAAH^−/− mice

REGION	Vehicle	THC	Anandamide
Caudate-Putamen	1.3 ± 0.13	0.82 ± 0.11^*	0.95 ± 0.09
Globus Pallidus	2.69 ± 0.28	1.55 ± 0.12^*	2.31 ± 0.18
Hippocampus	1.08 ± 0.10	0.49 ± 0.07^*	0.88 ± 0.06
Substantia Nigra	3.61 ± 0.44	2.25 ± 0.20^*	3.11 ± 0.29
PAG	0.76 ± 0.10	0.43 ± 0.07^*	0.57 ± 0.06
Cerebellum	1.79 ± 0.16	1.19 ± 0.12^*	1.69 ± 0.18

Brain sections were assayed as described in Methods.

Data shown are mean specific [³H]WIN55,212-2 binding values (pCi/g) ± SEM from 8-12 mice per group

p<0.05 vs. vehicle treated animals, one-way ANOVA with a post-hoc Dunnett’s test.