Skip to main content
. Author manuscript; available in PMC: 2022 Oct 18.
Published in final edited form as: Mol Cancer Ther. 2022 Aug 2;21(8):1306–1317. doi: 10.1158/1535-7163.MCT-21-0598

Table 1: Ribociclib pharmacokinetic parameters summary in mice bearing mouse tumor #2416 (n=7).

AUC-0–24h, Area under concentration-time curve from time zero to 24 h after dose; tECF, tumor extracellular fluid.

Parameters [Unit] Mean Estimates (SD)
Half-life [h] 4.26 (0.737)
Unbound Plasma AUC0–24h [ng × h/mL] 5820 (926)
tECF AUC0–24h/unbound Plasma AUC0–24h 0.162 (0.119)