. Author manuscript; available in PMC: 2023 Jan 25.

Published in final edited form as: Addiction. 2022 Oct 12;118(2):317–326. doi: 10.1111/add.16056

Table 4.

Sensitivity analyses, relationship of cannabis use status to SARS-CoV-2 infection.

	Sensitivity analysis 1: Using initial cannabis use status rather than time-varying status		Sensitivity analysis 2: Excluding time when persons were current or former smokers		Sensitivity analysis 3: Case-positive, control-test-negative approach.^a

	Adjusted Hazard Ratio (95% Confidence Intervals)				Adjusted Odds Ratio (95% Confidence Intervals)

Cannabis use status	Model 1^b	Model 2^c	Model 1^b	Model 2^c	Model 1^b	Model 2^c

Current	0.71 ( 0.60,0.83)^*	0.71 ( 0.60,0.83)^*	0.59 ( 0.46,0.76)^*	0.59 ( 0.46,0.77)^*	0.73 ( 0.60,0.90)^*	0.76 ( 0.61,0.93)^*
Recently quit	0.92 ( 0.81,1.04)	0.97 ( 0.85,1.10)	0.92 ( 0.81,1.05)	0.96 ( 0.84,1.09)	0.77 ( 0.68,0.87)^*	0.83 ( 0.73,0.94)^*
Non-user	1.00 (reference)	1.00 (reference)	1.00 (reference)	1.00 (reference)	1.00 (reference)	1.00 (reference)

Logistic regession model that includes all COVID tests during follow-up, stratified by (conditioned on) calendar date of the test. This analysis only includes persons who received at least one test. The cannabis status of persons who tested positive on a given day is compared to the cannabis status of persons who tested negative on the same day.

Model 1 is adjusted for age (21 categories: <19, 19–21, one for each year of age up to 39, 40+), race/ethnicity, neighborhood deprivation index, insurance payor, and primary KPNC facility.

Model 2 is adjusted for all covariables in Mode1 one plus body mass index, pre-existing diabetes and hypertension, parity, and tobacco smoking status.

Significant at p<=0.05