Fig. 4. Associations of the polygenic score for verbal learning (PGSVL) with activation in the right BA19 during the 2-back working memory task in a sample of N = 435 healthy adults (upper panel left view and lower panel right view).
Results are thresholded at peak-level p < 0.001 and masked for significantly increased activity during 2-back relative to 0-back. Rendered image illustrates clusters in which activity is negatively correlated with the PGSVL (the right cluster survives correction for multiple comparisons at BA19; MNI coordinates x = 45, y = −64, Z = 10; FWE corrected p = 0.016). Left in the figure is left in the brain.