Table 2.
Interrupted time series analysis results for behavioral and depression symptoms among long-stay nursing home residents with Alzheimer’s disease and related dementias pre-COVID-19 and during the COVID-19 pandemic.
| Behavioral symptoms (ARBS ≥ 1) |
Depression Symptoms (PHQ-9 ≥ 10) |
|||
|---|---|---|---|---|
| Est. | 95% CI | Est. | 95% CI | |
|
| ||||
| Period 1 (Jan 2018- Feb 2020): Pre-COVID-19 | ||||
|
| ||||
| % Symptoms at beginning of period 1 (Jan 2018) | 20.0 | 2.9 | ||
|
| ||||
| Slope during pre-COVID-19 period | 0.002 | −0.04, 0.04 | 0.01 | −0.01, 0.03 |
|
| ||||
| Period 2 (Mar 2020 – Jun 2021): During COVID-19 | ||||
|
| ||||
| Slope during COVID-19 period | 0.05 | −0.02, 0.12 | 0.04 | 0.02, 0.06* |
|
| ||||
| Slope change pre- and during COVID-19 | 0.05 | −0.04, 0.14 | 0.03 | 0.004, 0.06* |
|
| ||||
| % Symptoms at end of period 2 (Jun 2021) | 19.9 | 4.0 | ||
Est. = Estimate, 95% CI = 95% Confidence Interval, ARBS = Agitated Reactive Behavior Scale, PHQ-9 = Patient Health Questionnaire-9
*
p < 0.05
**
p < 0.001
Residents with diagnoses of Huntington’s disease, Tourette syndrome, or schizophrenia were excluded. Prevalence reported in the predicted percent from the interrupted time series model.