Table 1.
Discovery | Replication | Meta-analysis (discovery and replication) | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
|||||||||||
ID† | rsID | Closest gene | OR (95% CI) | P | Cochran’s Q P | OR (95% CI) | P | Cochran’s Q P | OR (95% CI) | P | Cochran’s Q P |
| |||||||||||
1:101210560:C:T | rs12091010 | EXTL2 | 0.82 (0.75–0.90) | 9.05E-06 | 4,83E-01 | 0.89 (0.82–0.97) | 5.35E-03 | 4.92E-01 | 0.86 (0.81–0.91) | 4.23E-07 | 4.47E-01 |
5:22659406:T:C | rs6888198 | CDH12 | 1.37 (1.23–1.54) | 1.95E-08 | 5,82E-01 | 1.02 (0.90–1.15) | 7.72E-01 | 7.18E-01 | 1.24 (1.05–1.45) | 2.41E-06 | 1.89E-02 |
10:91376299:T:C | rs943126 | PANK1 | 0.85 (0.78–0.92) | 3.10E-05 | 8,01E-02 | 0.92 (0.86–0.98) | 1.30E-02 | 3.87E-01 | 0.89 (0.85–0.94) | 4.93E-06 | 7.91E-02 |
The variant identifier corresponds to chromosomal position (hg19) followed by non-tested allele and tested allele.
Abbreviations: 95% CI: 95% confidence interval; OR: Odds ratio; P: P-value.