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A. TET1, TET2, and TET3 have 2, 3, and 3 transcriptional products respectively due to the alternative use of promoters, which are regulated by the alternative activation of enhancers. The green arrow indicates induction of expression; the red cross depicts inhibition of expression. B. The corresponding protein isoforms of TET1, TET2, and TET3. The structural domains of the proteins are indicated.
