Table 2.
Symptoms and GMA before and after Water Load Satiety Test in patients with Gastroparesis and Functional Dyspepsia
| Gastroparesis (n=282) |
Functional Dyspepsia (n=112) |
P-value¶ | |
|---|---|---|---|
| Mean (SD) | Mean (SD) | ||
| Water Load Test | |||
| Amount – mL | 378 (218) | 402 (226) | 0.23 |
| Abnormal (< 238 mL) – n (%) | 74 (26%) | 21 (19%) | 0.15 |
| Test length – min | 4.4 (2.5) | 4.1 (1.7) | 0.86 |
| Symptoms (VAS 0-100) | |||
| Fullness | |||
| Baseline | 28 (30) | 29 (32) | 0.98 |
| Change* | 37 (29) | 38 (32) | 0.44 |
| Hunger | |||
| Baseline | 30 (31) | 33 (32) | 0.43 |
| Change* | −5 (26) | −9 (24) | 0.07 |
| Nausea | |||
| Baseline | 27 (30) | 23 (28) | 0.17 |
| Change* | 5 (16) | 9 (21) | 0.17 |
| Bloating | |||
| Baseline | 28 (31) | 25 (29) | 0.34 |
| Change* | 12 (23) | 11 (20) | 0.54 |
| Abdominal discomfort | |||
| Baseline | 24 (29) | 20 (25) | 0.36 |
| Change* | 6 (16) | 8 (15) | 0.52 |
| GMA (Distribution of average - %) | |||
| Bradygastria (1-2.4 cpm) | |||
| Baseline | 49 (21) | 55 (20) | 0.02 |
| Change* | 0.7 (19.0) | −1.8 (19.7) | 0.63 |
| Normogastria (2.5-3.7 cpm) | |||
| Baseline | 20 (14) | 20 (14) | 0.86 |
| Change* | 1.5 (14.3) | 1.8 (15.0) | 0.93 |
| Tachygastria (3.8-10 cpm) | |||
| Baseline | 23 (14) | 19 (11) | 0.01 |
| Change* | −0.7 (11.8) | 1.2 (11.8) | 0.34 |
| Duodenal (>10-15 cpm) | |||
| Baseline | 7 (9) | 6 (10) | 0.08 |
| Change* | −1.5 (7.7) | −1.1 (7.4) | 0.40 |
*
Mean of 3 values taken at 10, 20 and 30 minutes after start of test – Baseline
¶
P-value derived from robust regression of outcome on GP type for baseline and robust regression of change in outcome on GP type and baseline value of outcome
GMA=gastric myoelectrical activity; GP=gastroparesis