Skip to main content
. Author manuscript; available in PMC: 2023 Jan 27.
Published in final edited form as: J Med Virol. 2023 Feb;95(2):e28445. doi: 10.1002/jmv.28445

Figure 3.

Figure 3.

Associations between salivary and nasopharyngeal microbiomes of SARS-CoV-2-positive patients and COVID-19 symptoms and age. (A) Alpha diversity, represented by richness, in saliva (red) and nasopharyngeal swab (blue) samples, for patients with a given symptom (dark red or dark blue) or without (light red or light blue). Age versus alpha diversity represented by Shannon index and richness of salivary (B) and nasopharyngeal (C) microbial communities. Principal coordinates (PC) analysis of weighted (D, E, left) and unweighted (D, E, right) UniFrac distances for salivary (D) and nasopharyngeal (E) microbial communities with age. The shaded areas in panels B and C indicate the 95% confidence intervals. Statistical significance was assessed using the Mann-Whitney U test for panel A, Spearman’s rank correlation coefficient for panels B and C, and PERMANOVA for panels D and E. *, P < 0.05.