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. Author manuscript; available in PMC: 2011 Apr 1.
Published in final edited form as: Eur J Hum Genet. 2010 Apr 21;18(10):1141–1147. doi: 10.1038/ejhg.2010.49

Table 2.

Suggestive LOD scores (LOD ≥1.86) for prostate cancer and for prostate and colon cancer (CCa) phenotypes

Phenotype
Prostate Cancer Prostate and Colon Cancer
Chromosome cM Left Flanking
SNP (bp)		 Right Flanking
SNP (bp)		 K&C1
LOD		 Dominant
HLOD2 		Recessive
HLOD2 		K&C1
LOD		 Dominant
HLOD2 		Recessive
HLOD2
Families with 1+ CCa (n=96)
11q25 162.07 rs1824832 (134313007) rs4430531 (134447835) 1.46 −0.06 0.22 1.94 −0.04 0.43
15q13-14 25.7 rs343913 (31133168) rs2033610 (31542203) 1.46 1.76 0.75 0.99 0.40 1.02
15q14 31.04 rs732165 (33141489) rs1989223 (33914397) 0.97 0.43 1.90 0.91 0.33 2.13
18q21 78.54 rs869224 (49231796) rs11455315 (49942953) 0.86 1.87 0.40 1.16 2.67 0.44
79.39 rs1145315 (49942953) rs1942569 (50997722) 0.7 1.84 0.39 1.08 2.82 0.59
19q13 87.21 rs897783 (56722974) rs1993104 (56932060) 1.21 1.10 1.96 1.14 0.55 0.79
Families with 2+ CCa (n=27)
1p32 80.95 rs731828 (54140841) rs1537323 (54255111) 0.53 0.53 2.45 0.75 −0.23 −0.47
1q31 202.08 rs1052238 (196901248) rs18924333 (197228191) 0.06 0.34 −1.51 0.12 0.06 2.19
11q14 93.01 rs1459937 (81203361) rs1459952 (81260386) 1.4 0.71 1.63 1.67 1.05 2.35
15q11 4.93 rs6576326 (22336292) rs975963 (22568288) 2.85 1.56 1.06 2.14 0.74 −0.13
15q13-14 25.7 rs343913 (31133168) rs2033610 (31542203) 2.38 2.22 1.36 1.86 0.52 1.65
15q14 31.04 rs732165 (33141489) rs1989223 (33914397) 2.45 0.77 3.47 2.29 0.41 3.88
1

K&C=Kong & Cox exponential allele sharing model;

2

Model = Affecteds-only model (see text).