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. Author manuscript; available in PMC: 2024 May 1.
Published in final edited form as: Adv Healthc Mater. 2023 Jan 31;12(12):e2203163. doi: 10.1002/adhm.202203163

Figure 6.

Figure 6

Analysis of (a) IFNγ, TNFα, IL-10, and (b) IL-2 in the supernatant after co-culturing the test articles with PBMC for 5 days. (c) Cytokine secretion of NYESO-specific CD8 T cells after 5 days of incubation with aAPC-shell or control groups. (d) CFSE-stained NYESO-specific T cell interacting with aAPC-shell (prepared with 18:1 Liss Rhodamine-PE). T cell maximized its contact area with the aAPC-shell, indicating the immune synapse was formed. Scale bar = 10 μm. N = 3. A two-tailed, unpaired t-test was applied. ***: 0.0001 <p-value < 0.001 (extremely significant). **: 0.001 < p-value < 0.01 (very significant). *: 0.01 < p-value < 0.05 (significant).