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. Author manuscript; available in PMC: 2023 Jun 5.
Published in final edited form as: Immunohorizons. 2023 Mar 1;7(3):213–227. doi: 10.4049/immunohorizons.2300008

Figure 7. An FRD only moderately modulates EAE disease severity, regardless of the route of ingestion or length of time on the diet.

Figure 7.

(A) Schematic of the experimental procedure. Mice were fed an FRD or ND for 4 or 12 weeks before EAE was induced and (B) disease severity monitored via scoring, survival, and area under the curve. N= 5 mice per group, Mantel-Cox log-rank test for survival. Mice were fed a fructose rich diet, ND, or fructose-supplemented water (30% w:v fructose) for 6 weeks before EAE was induced and (C) disease severity monitored via scoring, survival, and area under the curve. N=10 mice per group, 2-way ANOVA for EAE, Mantel-Cox log-rank test for survival.