Figure 1. Passive transfer of SARS hyperimmune antisera protects mice from challenge with SARS-CoV.
Left-hand y-axis: Mean viral titer in lungs is expressed as log10TCID50/g tissue with a lower limit of detection of 1.5 log10TCID50/g, error bars represent the SE, *p = 0.02 pairwise comparison of test groups to control group that received non-immune mouse serum
Right-hand y-axis: Reciprocal mean antibody titer, expressed as log2, is the dilution of serum antibody that neutralized 100 TCID50 of SARS-CoV. The lower limit of detection was ≤ 2, error bars represent SE, **p ≤ 0.0001 pairwise comparison of test groups to control group that received non-immune mouse serum.