Figure 6.
Binding nature of Poloxin and Thymoquinone to the Plk1 PBD. (A) Pocket #1 identified by SiteMap 2.3. (B) Proposed mechanisms of PBD inhibition by Poloxin and Thymoquinon. (C-D) Proposed binding modes of Poloxin (C) and Thymoquinone (D).
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