Table 1.
Compound | PBD inhibitory activitya | Kd (μM) |
---|---|---|
1 | High | 0.445 |
2 | Moderate | 2.7 (estimated) |
3 | No activity | - |
4 | Not determined | - |
Measured by an ELISA-based Plk1 PBD competition assay.
Compound | PBD inhibitory activitya | Kd (μM) |
---|---|---|
1 | High | 0.445 |
2 | Moderate | 2.7 (estimated) |
3 | No activity | - |
4 | Not determined | - |
Measured by an ELISA-based Plk1 PBD competition assay.