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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: ACS Med Chem Lett. 2010;1(3):110–114. doi: 10.1021/ml100020e

Table 3.

Differences in the PBD Binding between PLHSpT and PPG

Interaction PLHSpT PPG
Electrostatica His 538, Lys 540 His 538
Hydrogen bonding Trp 414 (2), Asp 416, Leu 491, Arg 516 Trp 414 (2), Leu 491, Lys 540,
Hydrophobic Phe 535 -
π-π stacking No Trp 414
a

Electrostatic interaction can be considered as strong hydrogen bond interaction.