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. Author manuscript; available in PMC: 2007 Jun 21.
Published in final edited form as: J Neurosci. 2006 May 24;26(21):5673–5683. doi: 10.1523/JNEUROSCI.0860-06.2006

Figure 5.

Figure 5

Genes regulated in the cerebellum and detected in Bergman glia (BG) (clusters 1, 2) or white matter (clusters 3). Left, Differential expression between knock-out (KO) and wild-type (WT) lines is shown in pseudocolor with associated p values from a t test. Average values for Pittsburgh (P) and Merck (M) lines are shown. Right, ABA images show regional distribution of three selected transcripts. ML, Molecular layer; PL, Purkinje cell layer; GL, granule layer; WM, white matter. Genes from cluster 1 were predominantly expressed in BG, whereas cluster 2 and 3 genes were also detected in other cell populations. Several genes including Clud1, Srr, S100a1, Mobp, and Mbp are known glial markers. Asterisks show the position of Purkinje neurons. Arrows point to detectable signal. The blue bar in the top left image represents ~100 μm. All images are copied and modified with permission from Allen Institute for Brain Science.