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. Author manuscript; available in PMC: 2023 Oct 23.
Published in final edited form as: J Proteome Res. 2023 Sep 11;22(10):3149–3158. doi: 10.1021/acs.jproteome.3c00177

Figure 1.

Figure 1.

Schematic of the DO-MS pipeline version 2.0. A schematic of the processing and intermediate steps of the updated DO-MS pipeline. Input files (blue) in the raw format are searched by a search engine (the default one is DIA-NN13) and converted to mzML using a custom version of the ThermoRawFile parser.41 The search report from DIA-NN and the mzML are then used by the post-processing step to analyze and display data about MS1 and MS2 accumulation times, TIC information, precursor-wise signal-to-noise levels, and MS1 features.