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. Author manuscript; available in PMC: 2023 Nov 10.
Published in final edited form as: Nat Genet. 2023 Oct 9;55(11):1854–1865. doi: 10.1038/s41588-023-01522-8

Fig. 7 |. Genetic correlations vary across disease subtypes defined by distinct topics.

Fig. 7 |

a, Excess genetic correlations for pairs of 15 disease subtypes or diseases (9 disease subtypes (denoted with asterisks) + 6 diseases without subtypes), relative to genetic correlations between the underlying diseases. Full square with asterisk denotes FDR < 0.1; less than full squares have area proportional to z-scores for difference. Grey squares denote NA (pair of diseases without subtypes or pair of same disease subtype or disease). b, Genetic correlations between the underlying diseases. Full circle denotes |z-score| > 4 for nonzero genetic correlation; less than full circles have area proportional to |z-score|. Numerical results are reported in Supplementary Table 14.