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. Author manuscript; available in PMC: 2010 Sep 22.
Published in final edited form as: Hum Genomics. 2005 Sep;2(3):158–167. doi: 10.1186/1479-7364-2-3-158

Figure 2.

Figure 2

Average fitness of recombinants between proteins from two diverging populations over the course of evolution. Averages of the same number of high-, medium-, and low-designable structures are represented as in Figure 1, except that the average of the better of the two reciprocal recombinants is shown with a solid symbol, while the average of the worse reciprocal recombinant is shown with a hollow symbol. Populations of size 1,000 were equilibrated for 10,000 generations prior to duplication and divergence for a further one million generations, and sequences were recombined at the midpoint.