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. Author manuscript; available in PMC: 2010 Sep 22.
Published in final edited form as: Hum Genomics. 2005 Sep;2(3):158–167. doi: 10.1186/1479-7364-2-3-158

Figure 4.

Figure 4

The average fitness of co-selected protein pairs as a function of the number of shared contacts between the pairs. Populations of size 1,000 were equilibrated for N generations under a co-selection regime (see methods). The fitness values were averaged across all structure pairs with the same number of shared contacts. Since there was no correlation between fitness of co-selected pairs and the designabilities of the structures in the pair, the fitnesses shown here were average over all possible structure pairs regardless of designability.