Skip to main content
. Author manuscript; available in PMC: 2023 Dec 8.
Published in final edited form as: Cancer Immunol Immunother. 2023 Oct 17;72(12):3985–3999. doi: 10.1007/s00262-023-03530-3

Figure 5.

Figure 5.

Flow cytometric analysis of CD8+ T-cells and surface markers associated with T-cell exhaustion in TILs from tumors. TILs were isolated from tumors derived from mice treated with corn oil (control), DIM-3-Br-5-OCF3 (2.5 mg/kg/d) and DIM-3,5-Cl2 (2.5 mg/kg/d). flow cytometric analysis using specific antibodies were used to determine the percentage of cells expressing PD1 (A), 2B4 (B), TIGIT (C) and TIM3 (D). Significant (p<0.05) induction or inhibition is indicated (*) and results are expressed as means ± SD for at least 4 separate mice per treatment group.