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. Author manuscript; available in PMC: 2024 Feb 14.
Published in final edited form as: J Med Chem. 2023 Aug 10;66(16):11040–11055. doi: 10.1021/acs.jmedchem.3c00221

Figure 3:

Figure 3:

(A) Structures of MPI60 and MPI61. (B) In vitro MPro inhibition curves of MPI60 and MPI61. (C) Cellular MPro inhibition curves of MPI60 and MPI61 in 293T cells transiently expressing MPro-eGFP. (D) SARS-CoV-2 (USA-WA1/2020) inhibition curves of MPI60 and MPI61 in Vero E6 cells.