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. Author manuscript; available in PMC: 2024 Oct 14.
Published in final edited form as: Nat Biotechnol. 2024 Jan 2;42(10):1581–1593. doi: 10.1038/s41587-023-02033-x

Extended Data Fig. 9 ∣. Stabl’s performance on synthetic data with binary outcomes.

Extended Data Fig. 9 ∣

Synthetic datasets with binary outcome variables were generated as described in Fig. 3. Sparsity (S^), reliability (FDR and JI), and predictivity (RMSE) performances of StablSRM (red box plots) compared to the respective SRM (grey box plots) as a function of the sample size (n, x-axis) for StablL (a), StablEN (b), StablSGL (c), and StablAL (d). Scenarios with 25 informative features and uncorrelated (left panels) or intermediate feature correlation structures (Spearman R ~ 0.5, right panels) are shown. Boxes in box plots indicate the median and interquartile range (IQR), with whiskers indicating 1.5 × IQR.