Figure 9. Fluoxetine attenuates repetitive behaviors and selectively reverses circuit deficits in NDN mice.
NET-KO mice were treated with fluoxetine (20 mg/kg i.p.) two hours after treatment withαMT. a) Fluoxetine reduced stereotypic behaviors and attenuated the excessive grooming observed in NDN-mice. b) Treatment with fluoxetine decreased the elevated FrA-striato and VTA-striatal circuit coherence observed in NDN mice; n= 5.