Figure 2.

Associations of prenatal acetaminophen exposure and (a) change in vocabulary count (number of words produced), (b) mean length of three longest utterances (number of morphemes produced, M3L), and (c) complexity (number of more complex sentences produced) measured using the CDI at 26.5-28.5 months.^a More acetaminophen use during the second and third trimesters, and throughout pregnancy, was associated with a decrease in vocabulary size. Increased acetaminophen use in the second and third trimesters was associated with a decrease in M3L. Prenatal acetaminophen exposure was not related to complexity scores.

^aModels were adjusted for child sex, age at assessment, maternal parity (nulliparous vs. ≥1), maternal education (<bachelor’s degree vs. ≥bachelor’s degree), and mean stress and depression scores during pregnancy.

†p<0.10,*p<0.05