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Postulated phenotypic changes undergone by breast cancer cells during EMT
| Loss of epithelial markers | Gain of mesenchymal markers |
|---|---|
| E-cadherin (CDH1) | vimentin |
| γ-cadherin | fibronectin |
| zonula occludens-1 (ZO1) | N-cadherin (CDH2) |
| Occluding | α-smooth muscle actin (α-SMA) |
| cytokeratin 8, cytokeratin 18 |
References: Li et al., 2009, Moen et al., 2009
