Table 1:
Top SNP by smoking interaction effects identified after BICS correction. SNP, single nucleotide polymorphism; Chr:BP, chromosome and base pair in GRCh37 coordinates; MAF, minor allele frequency; OR, odds ratio; Pint, p-value for interaction effect
| SNP | Chr:BP | MAF | OR, Never-Smokers | OR, Ever-Smokers | Pint |
|---|---|---|---|---|---|
| rs77196339 | 2:192442474 | 0.04 | 2.31 (1.69,3.15) | 0.53 (0.3,0.91) | |
| rs145440394 | 10:79833802 | 0.08 | 1.65 (1.26,2.15) | 0.6 (0.4,0.9) | |
| rs117732931 | 14:78999105 | 0.05 | 1.75 (1.3,2.35) | 0.58 (0.36,0.93) | |
| rs138130320 | 6:84011804 | 0.01 | 3.21 (1.62,6.34) | 0.25 (0.05,1.3) | |
| rs12715476 | 3:5548037 | 0.41 | 0.76 (0.64,0.91) | 1.25 (1.01,1.56) |