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Limiting dilution transplantation in secondary SCID mouse
| Tumors/injection sites | TIC frequency | p-value (vs. vehicle) | |||
|---|---|---|---|---|---|
| cells injected | 50,000 | 5,000 | 500 | ||
| Vehicle | 8/8 | 8/8 | 6/8 | 1/152 | |
| IB-DNQ | 8/8 | 8/8 | 2/8 | 1/546 | 0.055 |
| ATN-224 | 8/8 | 5/8 | 3/8 | 1/1586 | 0.0002 |
| Combo | 5/8 | 1/6 | 0/6 | 1/20391 | 2.6e-15 |
