Skip to main content
. Author manuscript; available in PMC: 2011 May 27.
Published in final edited form as: Biol Blood Marrow Transplant. 2009 Oct;15(10):1143–1238. doi: 10.1016/j.bbmt.2009.06.019

Pathogen: Bordetella pertussis

Indication First Choice Alternatives
Immunization against pertussis for adult or pediatric HCT recipients Acellular pertussis vaccine
  • Initial dose at 6–12 months post-HCT

  • A total of 3 doses should be given at least 1 month apart

Azithromycin orally daily for persons with incomplete vaccination series
Adults and adolescents: 250 mg
Pediatrics: 5 mg/kg daily
Postexposure prophylaxis for adult or pediatric HCT recipients, regardless of vaccination status Azithromycin:
Adults and adolescents: 500 mg for 1 day then 250 mg daily for 4 days
Pediatrics: 10 mg/kg loading dose then 5 mg/kg daily for 4 days