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. Author manuscript; available in PMC: 2011 Feb 1.
Published in final edited form as: Hum Brain Mapp. 2010 Feb;31(2):210–221. doi: 10.1002/hbm.20858

Figure 2.

Figure 2

Mean basal ganglia responses to gains, penalties, and no change feedback. For the three SNPs depicted (rs10494996, rs2841608, rs2841616), gains elicited robust activation in individuals possessing two copies of an allele previously associated with antidepressant response (“protective variant”). Note that for rs10494996, individuals homozygous for this allele were grouped with heterozygotes to increase sample size in the protected group (AA homozygotes: n = 2; AG heterozygotes: n = 8; GG homozygotes: n = 21).