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. Author manuscript; available in PMC: 2010 Nov 26.
Published in final edited form as: J Neurosci. 2010 May 26;30(21):7249–7257. doi: 10.1523/JNEUROSCI.6341-09.2010

Figure 3. Oral administration of CHZ improves motor performance in tottering mice.

Figure 3

(A) The performance of tg/tg (n=10, orange symbols) and +/+ mice (n=11, black symbols) was evaluated daily using an accelerating rotarod paradigm. CHZ treatment is denoted with the vertical bar. CHZ improved the motor performance of tg/tg, but not wild type mice.

(B) Maximum speed achieved before CHZ treatment (average of 5 days), during treatment (CHZ, average of 2 weeks) and after terminating treatment (Post, average of the last 5 days) for +/+ and tg/tg mice. (***) p<0.001 (One-way ANOVA, followed by Bonferroni correction), “n.s.” denotes not significant.