Table 3.

Medication – effect pairs with the ten highest EBGM estimates

Medication	Effect	nm, e	nm	ne	em, e	RRRm, e	EBGMm, e	Posterior null hypothesis probability
antihistamine	Decreased allergy symptoms	3	5	4	0.15	20.25	1.72	0.030
narcotic analgesic	Physical pain relief	7	9	25	1.67	4.20	1.53	0.006
Hypoglycemic	Helps control blood sugar	2	2	4	0.06	33.75	1.30	0.101
Contraceptive devices	Decreases menstrual period/PMS symptoms	2	3	3	0.07	30.00	1.29	0.103
antidepressant	Controls emotions/decreases volatility/moodiness	7	29	10	2.15	3.26	1.28	0.017
CNS stimulant	Increases energy level/alertness	6	10	25	1.85	3.24	1.21	0.029
Nonbarbiturate Hypnotic	Increased ability to sleep	2	3	6	0.13	15.00	1.18	0.12
vitamin supplement	Increases energy level/alertness	5	8	25	1.48	3.38	1.17	0.045
Antianxiety	Decreases stress/anxiety	2	2	10	0.15	13.50	1.16	0.124
herbal supplement	Helps control blood sugar	2	5	4	0.15	13.50	1.16	0.124

n_{m, e}- Number of medication m and positive effect e reports

n_m: Number of medication m reports

n_e: Number of effect e reports

e_{m, e}: Expected number of medication m and positive effect e reports if reported independently.

RRR_{m, e}: Relative Reporting Ratio for the medication m and positive effect e pair

EBGM_{m, e}: Empirical Bayes Geometric Mean of the posterior distribution of Λ_{m, e}