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. Author manuscript; available in PMC: 2010 Dec 9.
Published in final edited form as: J Neurosci. 2010 Jun 9;30(23):7900–7909. doi: 10.1523/JNEUROSCI.1507-10.2010

Figure 6.

Figure 6

Compilation of the effects of all manipulations on EPSC amplitudes for all neurons included in this study. The numbers in parentheses represent the total number of VTA DA neurons in which observations were made during each manipulation. Gray circles indicate EPSCs evoked by stimulation of the PPN, whereas, black circles represent EPSCs evoked via stimulation of the rostral VTA (intra-VTA). “Control” indicates either no injection 24 hr prior to brain slice preparation, or those responses from animals receiving a single saline injection. Note that PPN-evoked EPSCs were insensitive to JTx and did not demonstrate 66Hz-, or DHPG-induced LTD unless measured in VTA DA neurons obtained from cocaine- or Δ9-THC-treated animals. In addition, Δ9-THC exposure did not appear to increase the likelihood of intra-VTA-evoked LTD expression above that observed under control conditions.