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. Author manuscript; available in PMC: 2007 Jun 25.
Published in final edited form as: Br J Pharmacol. 2004 May;142(2):257–266. doi: 10.1038/sj.bjp.0705778

Figure 4.

Figure 4

WIN-2 does not inhibit stimulated cAMP accumulation or stimulate cAMP accumulation on its own: (a) Assessment of the effect of 10 min pretreatment with WIN-2 on 15min treatment with 1 μM forskolin-, 10 μM isoproterenol- or 10 μM PGE2-stimulated cAMP accumulation in the continued presence of WIN-2 (n=3, all conditions). (b) WIN-2 and AEA, at concentrations that evoke CGRP release, were exposed to TG neurons for 10 min to determine their effects on cAMP accumulation (n=6, P<0.001 vs baseline).