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. Author manuscript; available in PMC: 2010 Sep 8.
Published in final edited form as: Mol Cell Biol. 2010 Jun 1;30(15):3779–3794. doi: 10.1128/MCB.01578-09

TABLE 2.

Genetic interactions between dVHL and Rab5 in the lumen formation phenotypea

Genotype No. of embryos % normal % with dorsal trunk lumen phenotype (convoluted + dilated)
UAS-lazZ/+; UAS-dVHLi, btl-GAL4/+ 24 63 37
UAS-YFP::Rab5wt/+; UAS-FLP, btl-GAL4/+ 16 100 0
UAS-YFP::Rab5wt/+; UAS-dVHLi, btl-GAL4/+ 18 61 39
UAS-YFP::Rab5CA/+; UAS-FLP, btl-GAL4/+ 17 100 0
UAS-YFP::Rab5CA/+; UAS-dVHLi, btl-GAL4/+ 23 87 (A*) 13 (A*)
UAS-YFP::Rab5DN/+; UAS-FLP, btl-GAL4/+ 17 76 24
UAS-YFP::Rab5DN/+; UAS-dVHLi, btl-GAL4/+ 21 33 (B*) 67 (B*)
a

UAS-lacZ and UAS-FLP are used as neutral UAS transgenes for normalizing the effective Gal4 protein dosage. Statistical analyses used two-sample t tests for percentages.

*

modest significance (P < 0.1);

A

P = 0.065;

B

P = 0.066.