Table.

Virally Transduced Genes for Regeneration of Craniofacial Tissues

Gene	Application	Virus	References
BMP-4	Bone repair	Retrovirus, Adenovirus	Shen 2004, Wright 2002, Lin 2006
BMP-6	Bone repair	Adenovirus	Jane 2002
BMP-9	Bone repair	Adenovirus	Alden 2000
Shh	Bone repair	Retrovirus	Edwards 2005
caAlk2	Bone repair	AAV	Ulrich-Vinther 2007
VEGF	Bone repair, Condylar growth	Retrovirus, Adenovirus, AAV	Tarkka 2003, Rabie 2007, Jiang 2008
BMP-2	Bone repair, Chondrogenesis	Retrovirus, Adenovirus	Lee 2002, Chang 2003, Hu 2007, Smith 2000
BMP-7	Bone repair, Chondrogenesis	Retrovirus, Adenovirus	Jin 2003, Krebsbach 2000, Hidaka 2001
TGF-B1	Chondrogenesis	Retrovirus, Adenovirus, AAV	Lee 2001, Smith 2000, Zhao 2002, Pagnotto 2007
SOX9	Chondrogenesis	Retrovirus, Adenovirus, AAV	Li 2004, Cucchiarini 2007
IGF-1	Chondrogenesis	Adenovirus, AAV	Smith 2000, Izal 2008
GDF5	Chondrogenesis	Adenovirus	Feng 2008
AQP-1	Salivary gland repair	Adenovirus, AAV	Baum 2006
PDGF-B	Wound healing, Bone repair	Retrovirus, Adenovirus	Breitbart 2001, Jin 2004

BMP, bone morphogenetic protein; Shh, sonic hedgehog; caAlk2, constitutively active activin-like kinase 2; TGF-β1, transforming growth factor beta 1; IGF, insulin-like growth factor; GDF, growth and differentiation factor; AQP, aquaporin; PDGF, platelet-derived growth factor.

(Alden et al., 2000; Baum et al., 2006; Breitbart et al., 2001; Chang et al., 2003; Cucchiarini et al., 2007; Edwards et al., 2005; Feng et al., 2008; Hidaka et al., 2001; Hu et al., 2007; Izal et al., 2008; Jane et al., 2002; Jiang et al., 2008; Jin et al., 2004; Jin et al., 2003; Krebsbach et al., 2000; Lee et al., 2002; Lee et al., 2001; Li et al., 2004; Lin et al., 2006; Pagnotto et al., 2007; Rabie et al., 2007; Shen et al., 2004; Smith et al., 2000; Tarkka et al., 2003; Ulrich-Vinther, 2007; Wright et al., 2002; Zhao et al., 2002)