Table 2.
Frequency of 5-HTTLPR and CRHR1 genotypes.
| 5-HTTLPR genotype | 5-HTTLPR genotype and rs25531 | Functional classification Hu et al | ||||
|---|---|---|---|---|---|---|
| N | Percent | N | Percent | |||
| LL | 598 | 55.78 | LALA | 292 | 27.2 | high |
| LALG | 269 | 25.1 | intermediate | |||
| LGLG | 37 | 3.5 | low | |||
| SL | 359 | 33.49 | SLA | 243 | 22.7 | intermediate |
| SLG | 116 | 10.8 | low | |||
| SS | 66 | 6.16 | 66 | 6.2 | low | |
| LXL | 35 | 3.26 | LAXL | 20 | 1.9 | |
| LGXL | 15 | 1.4 | ||||
| SXL | 8 | 0.75 | 8 | 0.8 | ||
| LVL | 6 | 0.56 | LAVL | 3 | 0.3 | |
| LGVL | 3 | 0.3 | ||||
| N total | 1072 | 1072 | ||||
| CRHR1 rs110402 | CRHR1 TCA Haplotype | ||||
| AA | 87 | 7.2 | 0 Alleles | 577 | 48.8 |
| AG | 544 | 44.8 | 1 Alleles | 519 | 43.9 |
| GG | 582 | 48.0 | 2 Alleles | 87 | 7.3 |
| N total | 1234 | ||||
| SERT * TCA Haplotype Risk | |||||
| No Risk Alleles | 286 | 24.2 | |||
| S-allele only | 214 | 18.1 | |||
| CRHR1 risk only | 293 | 24.8 | |||
| Both Risk Alleles | 195 | 16.5 | |||