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. Author manuscript; available in PMC: 2012 Apr 1.
Published in final edited form as: J Cell Mol Med. 2011 Apr;15(4):747–755. doi: 10.1111/j.1582-4934.2010.01068.x

FIG 4. HEDSC Transplantation Increases Dopamine Concentrations in Mouse Striatum.

FIG 4

Dopamine concentrations (mean ±SEM) were measured in mice brains. In the first graph, animals not treated (unlesioned) with MPTP (n=5) are shown in the left column with baseline levels. In the middle column, MPTP lesioned mice showed an expected decrease in dopamine concentrations when given sham operations with PBS (n=8). In the right column, MPTP lesioned mice demonstrated rescued dopamine concentrations when treated with HEDSC transplantation (n=14), p<0.0001. A similar therapeutic effect of HEDSC is seen in the bottom graph by measuring the dopamine metabolite DOPAC concentrations in mice striatum, p=0.008.