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. Author manuscript; available in PMC: 2010 Nov 26.
Published in final edited form as: Oncotarget. 2010 Sep 1;1(5):329–338. doi: 10.18632/oncotarget.165

Figure 6. CD277 is preferentially expressed by APCs and tumor cells in the ovarian carcinoma microenvironment.

Figure 6

(A) Representative FACS analysis of CD277 expression on CD45+MHC-II+CD20− (solid), compared to that of other CD45+ cells (open) within the same human specimens. (B) FACS analysis of CD277 on CD4+CD25+ (regulatory + activated T cells) and total CD3+ T cells in a metastatic ovarian cancer tumor. Solid histograms indicate CD277 expression, open histograms represent isotype control staining. Identical results were obtained when primary tumors or ascites were analyzed for CD277 expression on T cells. (C) Representative FACS analysis of CD277 expression on CD45− cells in dissociated ovarian cancer specimens (mainly tumor cells; open thicked), compared to that in CD45+MHC-II+CD20− inflammatory leukocytes (solid) in the same specimen. Open dashed histograms represent isotype control staining. Comparable results were obtained in primary and metastatic tumors.