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. Author manuscript; available in PMC: 2010 Nov 9.
Published in final edited form as: Hum Genomics. 2010 Apr;4(4):226–237. doi: 10.1186/1479-7364-4-4-226

Figure 4.

Figure 4

Ratchet-like motion and hybrid tRNA configuration. (A) Superimposition of 30S (left) and 50S (right) subunits, as seen from the inter-subunit side. Classic-state subunits are shown in transparent grey, while the subunits of the hybrid-state ribosome are in solid yellow (30S) and blue (50S). (B) Close-up view of the 50S subunit showing the classic tRNA configuration. (C) Close-up view of the 50S subunit showing the hybrid tRNA configuration. The orientations of the subunits are shown as successive thumbnails on the left. This figure was reprinted from a paper in Molecular Cell by Agirrezabala et al.26 and is reproduced with permission from Elsevier.