Table 1.

Odds Ratio (OR) for the relationship between the minor alleles of SNPs and OSA in African-Americans^*

Cleveland Family Study		No BMI Adjustment			BMI Adjustment
	Minor Allele (%)	OR	95% CI	p-value	OR	95% CI	p-value
IL6-1111**	C (7)	1.44	(0.72–2.89)	0.30	1.70	(0.77–3.74)	0.19
IL6-1510**	C (8)	1.31	(0.59–2.90)	0.50	1.43	(0.53–3.88)	0.48
IL6-2892**	G (14)	1.29	(0.67–2.49)	0.45	1.14	(0.52–2.50)	0.74
IL6-3572†	T (40)	0.80	(0.51–1.26)	0.33	0.54	(0.25–1.17)	0.12
IL6-6021†	T (18)	0.63	(0.31–1.28)	0.20	0.24	(0.09–0.67)	0.0061
IL6-7592†	A (20)	1.14	(0.72–1.80)	0.58	1.24	(0.62–2.48)	0.54
Cardiovascular Health Study		No BMI Adjustment			BMI Adjustment
	Minor Allele (%)	OR	95% CI	p-value	OR	95% CI	p-value
IL6-1111**	C (8)	0.77	(0.30–1.96)	0.58	0.94	(0.35–2.58)	0.90
IL6-1510**	C (12)	2.37	(0.90–6.26)	0.08	2.60	(0.88–7.71)	0.09
IL6-2892**	G (9)	2.45	(0.81–7.47)	0.11	3.11	(0.90–10.75)	0.07
IL6–3572†	T (33)	1.02	(0.57–1.83)	0.94	0.88	(0.46–1.69)	0.70
IL6-6021†	T (13)	0.79	(0.37–1.70)	0.55	0.60	(0.26–1.40)	0.23
IL6-7592†	A (22)	1.07	(0.59–1.93)	0.83	1.25	(0.64–2.46)	0.51

^*Other covariates include age, age*age, age*sex, % African ancestry for Cleveland Family Study and age, age*age and sex for Cardiovascular Health Study.

^**Dominant mode of inheritance.

^†Additive mode of inheritance.