Structure and homology for the Drosophilia Groucho, TLE, and/or GRG protein family. The numbers above each box represent amino acid length for the domain identified at the top of the figure. A,B: The boxed numbers represent % homology for the Q or GP domain of Drosophilia Groucho or long GRG1-4 relative to GRG5 (A) Drosophilia Groucho or long TLE1-4 relative to AES(B). Percentage homology was calculated using global alignment with BLOSUM 62 scoring matrix. Amino acid sequence for the identified proteins are based upon the following NCBI accession numbers: Drosophilia Groucho (NP_733134), GRG1 (NP_035729.3), GRG2 (NP_062699.1), GRG3 (NP_033415.1), GRG4 (NP_035730.2), GRG5 (NP_034477.1), TLE1 (NP_005068.2), TLE2 (NP_003251.2), TLE3 (NP_005069.2), TLE4 (NP_008936.2) and AES (NP_001121.2).