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. Author manuscript; available in PMC: 2011 Jun 1.
Published in final edited form as: J Neurosci. 2010 Dec 1;30(48):16149–16159. doi: 10.1523/JNEUROSCI.2827-10.2010

Figure 9. CREB mutant mice exhibit a decrease in stress-activated cells that project to the VTA independent of previous drug conditioning.

Figure 9

While wildtype mice exhibit an increase in Fos activated cells that project to the ventral tegmental area [doubled labeled Fos/Flourogold (FG) cells] in the ventral (a) and dorsal (b) BNST, lateral hypothalamus (c) and the Infralimbic cortex (d), CREBαΔ mutant mice do not. No differences in Fos activated cells that project to the VTA were seen as a result of drug treatment during CPP. *p<.05, **p<.01, wildtype vs. mutant within the FST groups.